Generative Unconstrained Intelligence Drug Engineering (GUIDE) collaboration between U.S. interagency, academic and industry partners
| Agency | Department of Defense Department of the Army |
| Contracting office | W6qk Acc-apg |
| Place of performance | Frederick, MD |
| Type of notice | Special notice |
| Set-aside | None, open to all businesses |
| Response deadline | Oct 18, 2028 |
| Posted | Dec 1, 2025 |
| Solicitation number | W911SR-25-S-GUIDE |
| NAICS code | 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) |
Summary from the notice
W911SR-25-S-GUIDE Notice Type: Special Announcement Synopsis: This is a solicitation for parties interested in participating in projects sought by the The Joint Project Lead Chemical, Biological, Radiological, and Nuclear Defense Enabling Biotechnologies (JPL-CBRND-EB) (JPL EB). JPL EB has the mission to accelerate the delivery of medical countermeasures to the warfighter through the development and implementation of platform systems. Generative Unconstrained Intelligence Drug Engineering (GUIDE) is an integrated computational and experimental platform designed to accelerate medical countermeasure development. GUIDE harnesses the power of advanced simulation and machine learning to enable preparedness and facilitate rapid response to protect the warfighter from a diverse and dynamic threat space. GUIDE impacts the discovery and design of biological products (e.g., monoclonal antibodies and vaccines) as well as small molecule drugs by simultaneously optimizing critical quality attributes of safety, efficacy, manufacturability and pharmacokinetics/pharmacodynamics while concurrently accounting for critical design attributes affecting developability and biophysical properties. GUIDE is a collaboration between U.S. interagency, academic and industry partners and is closely linked to the Accelerated Antibodies, Rapid Access to Products in Development (RAPID), Vaccine Acceleration by Modular Progression (VAMP), and Rapid Acquisition and Investigation of Drugs for Repurposing (RAIDR…
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Details copied from the public SAM.gov notice. BidFox is not connected to SAM.gov or the U.S. Government, so check the official notice before you bid.